What is Carba-NAD (CAS 112345-60-5)?
Carba-NAD (CAS 112345-60-5) is a synthetic analogue of the naturally occurring coenzyme NAD (Nicotinamide Adenine Dinucleotide), a crucial molecule involved in numerous metabolic processes within the body.
Unlike NAD, Carba-NAD features a methylene group substitution for an oxygen atom adjacent to the anomeric linkage bearing nicotinamide, rendering it inert in nicotinamide displacement reactions. This modification makes Carba-NAD an unreactive substrate
analogue for NAD-consuming enzymes, offering unique advantages for scientific research, particularly in the study of enzyme mechanisms and the development of pharmaceuticals.
What are the benefits and uses of Carba-NAD (CAS 112345-60-5)?
The distinct structural modification in Carba-NAD allows it to serve as a tool in biochemical and pharmaceutical research by providing insights into the interaction between NAD-consuming enzymes and their substrates.
This has implications for the development of new drugs, especially those targeting metabolic pathways and enzymatic reactions where NAD plays a key role.
Carba-NAD's stability and resistance to enzymatic reactions make it an invaluable compound for creating enzyme inhibitors or designing therapeutic agents that can modulate the activity of NAD-dependent enzymes.
Moreover, Carba-NAD's application extends beyond drug development. It is also used in diagnostic assays and analytical chemistry as a stable standard or reference compound to study enzyme kinetics and mechanisms. This can aid in identifying potential
drug targets and evaluating the efficacy of NAD-modulating compounds.
Product Documents
COA (Certificate of Analysis)
SDS (Safety Data Sheet)